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Dr. Parcells works with Poultry and Animal Health Companies to develop and test new vaccines, perform basic mechanism of action studies, and provide expertise in product development and testing. The projects in his laboratory range from the functional interactions of viral and cellular proteins as they relate to Marek's Disease Virus (MDV), a T-lymphoma-inducing herpesvirus of chickens. This work includes the study of MDV infection and pathogenesis, the evolution of MDV virulence, and the development and testing of vaccines for Marek's disease. Dr. Parcells has a strong interest in tumor immunology and tumor virology and vaccine development.
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The 2020 Nobel Prize in Physiology or Medicine has been awarded jointly to Harvey J Alter, Michael Houghton and Charles M. Rice “for the discovery of Hepatitis C virus.” the Nobel Committee noted that the trio's work helped explain a major source of blood-borne hepatitis that couldn't be explained by the hepatitis A and B viruses. Their work makes possible blood tests and new medicines that have saved millions of lives, the committee said. "Thanks to their discovery, highly sensitive blood tests for the virus are now available and these have essentially eliminated post-transfusion hepatitis in many parts of the world, greatly improving global health."